Nexium, Prevacid, Prilosec and Protonix are a popular and multibillion-dollar-a-year class of heartburn drugs known as proton-pump inhibitors. Researchers say they are perfectly safe, except when combined with Clopidogrel, the key anti-clotting ingredient in Plavix.
The study found patients who took both medications increased their risk of heart attack and stroke by 50%. Plavix is the most widely used drug in the world to prevent blood clots.
The findings of this study could affect millions of people. The FDA has not commented yet on the results of this study. The research was conducted by Medco Health Solutions Inc. and the Indiana University School of Medicine.