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But he's not alone. A neighborhood scout has stowed away, and together the two unlikely friends float away to exotic locales.
The film marks a big step for Pixar with their 10th studio film. This time around, it's available in both 2-D and the new Disney 3-D format.
So what's different in the 3-D version?
Producer Jonas Rivera explains to entertainment reporter George Pennacchio of ABC7 in Los Angeles.
"It was very important to us that it worked in both," said Rivera. "We started in 2-D, and we didn't want 3-D to change the way we cut the film or compose a shot. We wanted to tell the story, and put 3-D on top to enhance that story. So if you see it in 3-D, you feel more immersion, but still the same pace and emotion, so forth."
"Up" director Pete Docter agrees:
"We designed it first and foremost as a film," said Docter. "You're caught up in the story, the characters, hopefully 3-D - though it's cool - adds to it, and you're not conscious of things going, 'Booga booga' and breaking that wall. Hopefully you just get lost in the story."
"Up" is rated PG for some peril and action. It's in theaters Friday.