Agents worked with federal, state, and local law enforcement officials to target transnational gangs involved in crimes including human trafficking, drug and weapons smuggling, and identity theft.
"Operation Community Shield has progressed from a program that targeted individual gang members for arrest, prosecution and removal to a successful strategy of dismantling the violent transnational gangs themselves," said Department of Homeland Security Assistant Secretary for ICE John Morton.
There were 293 people arrested in the Los Angeles area.
ICE says 35 percent of those arrested have violent criminal histories. 16 were gang leaders.
The operation spanned 89 cities and ended on September 30.
City News Service and the Associated Press contributed to this report.