Melody Ross, 16, was gunned down around 10 p.m. on Oct. 30 shortly after the homecoming football game at Wilson High School where she was a student.
Investigators believe Ross was an innocent bystander who was shot during a confrontation between two groups of gang members.
The suspects are identified as Tom Love Vinson of Bellflower and Daivion Davis of Long Beach. Both are charged with one count of murder and two counts of attempted murder, according to the Los Angeles County District Attorney's Office.
The two were arraigned Friday at Long Beach Superior Court.
"In this particular instance, they're both direct-filed by the district attorney's office because the nature of the charges here being a murder and two attempted murders, as well as there's a gang allegation, which allowed to direct-file," explained prosecutor Dean Bengston.
The shooting also left two men wounded. They are expected to survive.
Investigators believe Vinson fired the handgun and that both suspects committed the crimes for a street gang.
Davis and Vinson remain in custody on $3 million bail each. According to the prosecution, the plan is to try them both at the same time.
If the two are convicted on all charges, they face a maximum of 130 years to life in prison.
Security was stepped up for Friday night's football game between Wilson and Jordan High School
Wilson High School's football players wore Melody Ross' initials on their helmets, and the W that signifies Wilson High School was turned upside down to honor their fallen fellow student. Wilson High beat Jordan High School 47-3 Friday night.
Eyewitness News Reporters Sid Garcia and Leanne Suter contributed to this story.