The homeowner, 45-year-old Glynna Rose Folkens, was inside the kitchen at the time, and the crash pinned her against a stove.
"I just heard a big bang, and then I come down to help these people, and this truck had come through the house. There was a lady right here that was leaning over the front of the truck," said neighbor Richard Appell.
Witnesses said it was tough getting both the homeowner and the driver out of the wreckage, and firefighters had to extricate both victims.
Both victims were rushed to a local hospital, but the homeowner died early Friday morning.
The one thing that is noticeably absent as police investigate the accident is skid marks. There's nothing to indicate that the driver did anything to slow down before slamming into a cinder block wall and eventually a house.
The impact sent big blocks of cinder block flying in all directions. They were scattered all over front lawns and car windows were shattered.
"It's like a war zone back there, just things everywhere," said neighbor Kent Morris.
Segura lives just up the block from the accident scene. Police said they will be looking at the teen's blood-alcohol level and his state of mind in the moments before the crash.
Police say the cause is still under investigation, but early evidence suggests Segura may have been attempting suicide.
Segura was hospitalized and his condition is not known. It was not clear whether he would face any charges.
The Associated Press contributed to this story.