This fall she'll star in the drama "Body of Proof," playing a brilliant surgeon who's been in a serious car accident and can now no longer operate. So she switches gears and becomes a medical examiner.
"Friends" alum Matthew Perry will hit the schedule mid-season in the comedy "Mr. Sunshine," playing the manager of a sports arena who happens to be going through a bit of a mid-life crisis. Allison Janney of "The West Wing," is his boss.
Rob Morrow and Joely Richardson star in Jerry Bruckheimer's legal drama "The Whole Truth," which will show cases from the perspectives of both the defense and the prosecution.
Michael Chiklis and Michael Imperioli also star in two new shows.
"No Ordinary Family," with Chiklis, is about a family whose plane crashes into the Amazon River and they emerge with superpowers.
Imperioli is on the other side of the law playing a "damaged but driven" detective in a homicide unit in "Detroit 1-8-7." It's on the schedule for 10 p.m. ET/PT on Tuesdays.
On a lighter note, "My Generation" is about high school classmates marking 10 years since their graduation.
And ABC's new comedy "Better Together" follows three couples in a family at various stages of their lives and relationships.
ABC's new midseason shows include "Off The Map," a medical drama set in a tiny town in a South American jungle, produced by "Grey's Anatomy" and "Private Practice" producer Shonda Rhimes, and the comedy "Happy Endings," about how friends of a couple will respond to their breakup.
ABC also announced Vanessa Williams from "Ugly Betty" will join the cast of "Desperate Housewives." "V," "The Bachelor" and "SuperNanny" will return at midseason.
Series not returning include "FlashForward," "Scrubs," "Better Off Ted," "The Deep End" and "Romantically Challenged.
City News Service contributed to this report.