"Our biggest and I believe best tour has been interrupted and we're all devastated," said manager Paul McGuinness.
The tour was to start in Salt Lake City on June 3. After that the band was scheduled to play in Anaheim, Calif., on June 6 and 7 followed by Denver on June 12 and Oakland, Calif., on June 16.
Bono hurt himself while training for the next leg of their tour, but specifics were not given. He has been released from the hospital and is at home recovering. His doctors recommend at least two months rest.
The band's debut gig at Britain's iconic Glastonbury festival was also canceled. A replacement headlining act has not been announced. The festival, which runs June 23-27, attracts more than 175,000 people.