Police in Peru say the Dutchman has confessed to killing Flores, but the newspaper reports that he told a reporter that he confessed because he was told he'd be sent back to the Netherlands.
"I was very scared and confused during the interrogations and wanted to get away," the paper quoted him as saying. "In my blind panic, I signed everything, but didn't even know what it said."
Prosecutors allege Van der Sloot killed Flores in his hotel room, where her body was found, with "ferocity and great cruelty." According to a transcript of the confession, he elbowed the young woman in the nose, strangled her with both hands, threw her to the floor, took off his bloodied shirt and asphyxiated her.
A self-avowed compulsive liar, Van der Sloot has several times given and retracted admissions of involvement in Holloway's disappearance.
In the meantime, van der Sloot's mother told ABC News that her son is psychologically disturbed and was capable of killing Flores.
"My son is sick in his head," Anita van der Sloot said.
However, Anita van der Sloot said she does not believe her son killed Holloway.
In an e-mail to ABC News, Anita tried to paint a different picture of her son.
"He is not the monster the (media) would like the world to see," she writes. "He is traumatized, depressed and has an addiction. He is not a murderer."
She told the paper he had called her several days before Flores' death, sounding paranoid.
"He said he was being followed. He had been arrested together with a girl and robbed. He was not making sense," the paper quoted her as saying.
The Associated Press contributed to this story.