They cheered the floats representing the countries of the region. Community groups and elected officials greeted the crowd.
Los Angeles police Chief Charlie Beck was on hand to show support.
Police patrolled the route through the Westlake District, but the parade was peaceful and there were no arrests.
Tensions have been high between police and some community members in the area since the officer-involved shooting of a Guatemalan man two weeks ago.
Do you want the Eyewitness News team to call you? Get a FREE Morning Wake-up Call and personalized weather report at abc7.com/wakeup