The two died after suffering head wounds. A third man, 19-year-old Marvin Gonzalez, was shot in the back.
Officials said the men were approached by two or three suspects who confronted them. They demanded to know what gang they were affiliated with, and one of the suspects opened fire.
If you have any information about this crime, you're urged to contact LAPD's Northeast Station at (213) 847-4261.
City News Service contributed to this report.