David Fincher's film about the birth, evolution and clashes behind Facebook raised its 10-day total to $46.1 million.
Katherine Heigl and Josh Duhamel's romance flick, "Life as we Know it" came in at a close second with $14.6 million. The movie follows the story of sparring guardians looking after an orphaned girl.
"Secretariat," the horse-racing drama starring Diane Lane, came in third with $12.6 million.
Wes Craven's serial killer thriller, "My Soul to Take" came in at No. 5 with a weak $7 million.
1. "The Social Network," $15.5 million.
2. "Life as We Know It," $14.6 million.
3. "Secretariat," $12.6 million.
4. "Legend of the Guardians: The Owls of Ga'Hoole," $7 million.
5. "My Soul to Take," $6.9 million.
6. "The Town," $6.4 million.
7. "Wall Street: Money Never Sleeps," $4.6 million.
8. "Easy A," $4.2 million.
9. "Case 39," $2.6 million.
10. "You Again," $2.5 million.
The Associated Press contributed to this report.
