Court records in Los Angeles show the couple's divorce was finalized by a retired judge on Wednesday.
Wilson, 56, filed for divorce in September, citing "irreconcilable differences." The couple, separated since June 2008, has twin 10-year-old sons.
Crowe, director of films such as "Jerry Maguire" and "Say Anything," won an Oscar for the screenplay for "Almost Famous." Wilson worked on the soundtracks of several of Crowe's film, and had a cameo in "Fast Times at Ridgemont High," which he wrote.
The Associated Press contributed to this report.