The incident happened Nov. 26.
Police said the woman was drinking at a bar called Godfather's, met a group of men and was led outside where she was assaulted in a Jeep Cherokee.
Two men are behind bars.
The two suspects who are still on the loose are both described as black, approximately 20 years old, 5 feet 8 inches tall and around 200 pounds.
If you have any information, you are asked to contact Tustin police at (714) 573-3200.