"Californication," which stars David Duchovny as writer Hank Moody, has been renewed for a fifth season by cable network Showtime.
Production on 12 new episodes of the hit comedy series is set to begin in the spring, it said in a statement.
The premiere of the fourth season of "Californication" Sunday was the show's most-watched, with more than one million viewers.
The current season includes guest appearances by Rob Lowe, rocker Tommy Lee, Zoe Kravitz, Madeline Zima, Stephen Tobolowsky and Carla Gugino.
"Californication" has won two Emmys for Best Cinematography. Duchovny, who played Agent Fox Mulder on "The X-Files" from 1993 to 2002, won a Golden Globe award for his role on the series in 2008 and was nominated again in 2009 and 2010.
The actor, who also won the prize for his "X-Files" part in 1997, did not receive a nod this year. The 2011 Golden Globes are set to take place on Sunday.