The romantic comedy "Just Go With It" debuted at No. 1 this weekend, pulling in about $31 million.
The movie stars Aniston and Sandler as friends posing as a soon-to-be divorced couple.
"Justin Bieber: Never Say Never," the concert documentary, came in a very close second, pulling in just over $30 million.
In fact the numbers are so close, the final rankings could change by Monday.
The Disney adventure "Gnomeo and Juliet" finished a strong third with $25.5 million.
The top 10 movies of the weekend were:
1. "Just Go With It," $31 million.
2. "Justin Bieber: Never Say Never," $30.3 million.
3. "Gnomeo & Juliet," $25.5 million.
4. "The Eagle," $8.6 million.
5. "The Roommate," $8.4 million.
6. "The King's Speech," $7.4 million.
7. "No Strings Attached," $5.6 million.
8. "Sanctum," $5.1 million.
9. "True Grit," $3.8 million.
10. "The Green Hornet," $3.6 million.