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OTRC: Joseph Gordon-Levitt has cancer in Seth Rogen comedy '50/50'

Seth Rogen in a still from his 2007 film, 'Knocked Up.' (Photo courtesy of Universal Pictures)

Seth Rogen's upcoming cancer comedy has been re-named "50/50" and will be released a week later than planned, on September 30, according to The Hollywood Reporter.

The story is based on screenwriter Will Reisener's real-life experience being diagnosed with cancer in his mid-20s. The script made the Black List a few years ago and Rogen showed interest in developing it, so the project will be produced by Seth Rogen, Evan Goldberg and Ben Karlin. Summit Entertainment acquired distribution rights in February 2010.

"It's rare to find a script that has you laughing and crying in equal measure, or a cast and director as perfectly suited to get the tone of this unique and moving film as perfectly right," Erik Feig, Summit's president of production, said in a statement.

The comedy has previously been named "I'm With Cancer" and "Live with It." Joseph Gordon-Levitt stars as the lead and Rogen will play his supportive friend. James McAvoy was originally slated to star in the film but dropped out.

The film also stars Anna Kendrick, Bryce Dallas Howard and Anjelica Huston. It was directed by Jonathan Levine ("The Wackness") and filming took place in Vancouver, Canada.

The release date was moved so that it wouldn't have to compete with a slew of male-friendly features like "Abduction," "Moneyball" and "Journey 2: The Mysterious Island." In its new release date, "50/50" is up against the Anna Faris comedy, "What's Your Number" and the Universal thriller "Dream House."

The film will be Rogen and Gordon-Levitt's first movie together. Rogen voices an alien in his upcoming comedy "Paul," which is about two British comic-book geeks traveling across the U.S. encounter an alien outside Area 51. "Paul" is slated for release on March 18, 2011.

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