The incident happened shortly after 2:30 a.m. Sunday near Eastern Avenue and Commerce Way.
The sheriff's department said deputies in one car were chasing a suspected drunk driver who veered into another patrol car.
Deputies in that car swerved to avoid a collision and hit a tree.
The deputies were taken to Los Angeles County USC Medical Center with non-life threatening head and leg injuries.
The suspected drunk driver was arrested later at his home.
