The troubled actor appeared on ABC's "Good Morning America" and continued to attack CBS producers of his sitcom for shutting down the show due to his off-set behavior.
Sheen told ABC News correspondent Andrea Canning that he planned to sue his bosses for breach of contract.
"Wouldn't you?" he said. "I've got a whole family to support and love. People beyond me are relying on that. I'm here to collect. They're going to lose. They're going to lose in a courtroom, so I would recommend that they settle out of court."
Canning asked Sheen whether the people who supplied him with drugs were out of his life.
"That's nobody's business," he said. "I think you know the answer to that."
Sheen claimed to be free of drugs and any addictions. ABC had Sheen's blood and urine tested for drugs by a certified laboratory. The results showed no drug use in the past 72 hours, but Sheen admits his past drug habit was excessive.
"Man, it was epic. The run I was on made Sinatra, Flynn, Jagger, Richards, all of them just look like, you know, droopy-eyed armless children," Sheen told Canning.
Asked if he was worried he would eventually overdose, Sheen's answer conveyed a sense of invincibility.
"I'm me. I just have a different constitution. I have a different brain. I have a different heart," he said. "I have tiger blood, man."
As for Sheen's very public outbursts, some of which have been labeled anti-Semitic, Sheen said that was all a joke.
"I didn't know you were so sensitive. Sorry if I offended you. I just thought, you know, after you wailing on me for eight years that I could take a few shots back. I didn't know you were going to take your little ball and go home and punish everybody in the process," he said.
In the aftermath of the interview on "Good Morning America," Sheen's long-time publicist, Stan Rosenfield, abruptly quit.
"I have worked with Charlie Sheen for a long time and I care about him very much," Rosenfield said in a statement. "However, at this time, I'm unable to work effectively as his publicist and have respectfully resigned."
Sheen also appeared on NBC's "Today" show. NBC interviewer Jeff Rossen appeared taken aback when Sheen said he wanted to be paid $3 million an episode to return to the show. He's reportedly paid $1.8 million an episode now, and is one of the highest-paid actors on TV.
While Sheen said in a radio interview last week that it would be impossible to do a ninth season of "Two and a Half Men" with the show's creators in charge, he said in the TV interviews he's ready to work another season.
He said CBS owes him an apology, "publicly, while licking my feet."
Experts say Sheen may be in a manic state.
"They often become incredibly grandiose, 'I'm on a drug that no one else can tolerate because it's so amazing and expansive, that anyone else's face would fall off his they had as much power and intensity as I had,'" said addiction psychologist Dr. Shahia Modir. "He really needs psychiatric stability."
Canning's full interview is slated to air Tuesday on a special one-hour edition of "20/20."
The Associated Press contributed to this report.