The pedestrian was struck on Martin Luther King Jr. Boulevard near Menlo Avenue.
The victim was leaving a party just after midnight when the car hit him. He was taken to the hospital but did not survive his injuries.
Police were trying to figure out if anyone saw the accident or could provide a description of the vehicle.
Anyone with information is urged to call police at 1 (877) LAPD-24-7 or 1 (877) 527-3247.