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OTRC: Rob Lowe, John Stamos 'endorsed' by Charlie Sheen

Charlie Sheen speaks to reporters in Los Angeles on March 2, 2011. / John Stamos speaks to OnTheRedCarpet.com in Los Angeles in September 2010. / Rob Lowe appears in a promotional photo for the ABC series 'Brothers and Sisters.' (ABC)

Rob Lowe and John Stamos have gotten Charlie Sheen's blessing to replace him on "Two and a Half Men"' after he was fired from the hit CBS show earlier this week following erratic rants he made against its co-creator.

Production on "Two and a Half Men" was suspended in January after Sheen underwent rehab for drug and alcohol addiction and halted in February after he insulted the show's co-creator Chuck Lorre during a radio interview.

Sheen, 45, had said in interviews last week that he is currently sober. Warner Bros. Television said in its firing letter on Monday, March 7 that he has "been engaged in dangerously self-destructive conduct and appears to be very ill." Sheen called his firing "illegal."

CBS and Warner Bros. have not announced what will happen with the show. Recent media reports named Lowe, 46, and Stamos, 47, as possible contenders to replace Sheen.

Lowe's spokesperson declined comment on the reports, when reached by OnTheRedCarpet.com. Stamos said weeks ago, after the show halted production, that he was not replacing the actor on "Two and a Half Men."

"I think they're both fabulous," Sheen told The 'Dan Patrick' radio show on Wednesday, March 9. "Rob's an old friend and a brilliant actor and he's a brilliant man. Would I would advise them to do is just make it their own. Don't think about what I'd done brilliantly on the show."

"I don't even know if they could call the guy 'Charlie' anymore," he added. "How does the show transition? Do they just do it without explaining it and hope people don't notice?"

Lowe was a former "bad boy" teen heartthrob and member of the "Brat Pack" in the 1980s, when he starred in films such as "St. Elmo's Fire." He has appeared on shows such as "The West Wing," "Brothers and Sisters" and recently, NBC's "Parks and Recreation." Stamos rose to fame as Uncle Jesse on the sitcom "Full House" and later went on to star in "ER." He can currently be seen on the FOX musical comedy series "Glee" in a recurring role.

Sheen said that he was partially glad that he was fired from "Two and a Half Men."

"There's a part of me that is, because now I'm a free agent to go pursue some things that are a little more creative than that slag pit of redudancy," he told Patrick. "And there's a part of me that kind of enjoyed taking all their money so I kind of have to find something between the two to make myself happy again."

Sheen began playing party-loving Charlie Harper on "Two and a Half Men" when the series premiered in 2003. Jon Cryer was cast as his character's straight-edge brother.

Charlie Sheen recently "half-apologized" to Cryer for calling him a "troll" because he did not contact him amid the turmoil. He said he wants to return to making movies and plans to star in a third big-screen "Major League" movie. He had starred in two previous installments that have become favorites among baseball fans.

UPDATE on March 10, 2011: A producer for "Parks and Recreation" said on Wednesday, March 9, that Lowe cannot replace Sheen on "Two and a Half Men" because he is bound under contract to continue to star in the NBC series. On Thursday, March 10, Sheen filed a $100 million lawsuit against Lorre and Warner Bros over his firing.

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