Strauss-Kahn is accused of attempting to rape the maid and forcing her to have oral sex in his room at the Sofitel hotel in New York City.
Two people familiar with the investigation told The Associated Press that DNA pulled from a substance on the maid's shirt matches the DNA sample Strauss-Kahn provided last week.
Strauss-Kahn's attorney has said evidence in this case will not be consistent with a forcible encounter. This may signal a defense based on consensual sex.
The one-time French presidential contender has been charged with a criminal sex act, attempted rape and sexual abuse and is free on $1 million bail, under house arrest at a lower Manhattan apartment.
The Associated Press contributed to this report.