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OTRC: Patrick Dempsey to leave 'Grey's Anatomy after season 8?

Patrick Dempsey appears in a promotional still for 'Grey's Anatomy.'

Is McDreamy leaving Seattle Grace next year?

"Grey's Anatomy" actor Patrick Dempsey reportedly told Italian Vanity Fair that the next season of the medical drama "will be my last." He added, "I don't know what will happen with the other characters, but for me, it's done."

The actor's spokesperson told OnTheRedCarpet.com, "He [Dempsey] was referring to the fact that his contract is up at the end of next season and we have no idea what the future holds." ABC had no comment on the matter.

Dempsey's co-star and on-screen love interest, Ellen Pompeo, has also hinted in recent interviews that she will make her exit once her contract is up next season, the show's eighth.

In a 2010 interview, the actress told Extra, "When my contract is up after Season 8, I would probably not renew. I think I've told all the stories I can tell as Meredith Grey."

She later clarified her remarks to TV Line in May saying, "No one has asked us [her fellow cast members] to come back after Season 8, so I couldn't presume that I'm coming back ... if I haven't been invited."

Dempsey will soon be seen on the big screen in "Transformers: Dark of the Moon," which is scheduled for release on July 1, 2011.

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