The issue hits comic book shops on Wednesday. But Spider-Man fans shouldn't worry too much about his future.
While the character is dying off in the "Ultimate Comics Spider-Man" series, he is still alive and well in Marvel's traditional stories.
The death, while dramatic, is not entirely unexpected. In November, Marvel said that the Ultimate Spider-Man was going to face an uncertain fate in the latest storyline by writer Brian Michael Bendis fittingly titled "The Death of Spider-Man," an eight-issue arc that saw the return of original series artist Mark Bagley. Bendis and Bagley had worked together on the series for 111 issues.
Bendis said that in issue No. 160 Peter Parker fights valiantly but will pass on, heroically, in a pitched fight.
The Associated Press contributed to this report.