It happened near Lassen Street at around 3 a.m. Sunday.
Police said a 29-year-old man was speeding in a sedan with a 24-year-old woman in the passenger seat.
As he reached a bend in the road, he lost control, crashing into a power pole, a fire hydrant and several other objects.
Both the driver and passenger died at the scene.
The crash also temporarily knocked out power to hundreds of homes.