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OTRC: Katherine Heigl stars in 'I Hate Balls' animal rights PSA - See video

Katherine Heigl appears in a still from a 2011 PSA for her 'I Hate Balls' campaign. (FunnyorDie.com)

Katherine Heigl is not afraid to joke that she "hates balls" for a good cause.

The "Knocked Up" actress and former "Grey's Anatomy" star is featured in a PSA advocating for pet owners to neuter their pets. The PSA is part of the Jason Debus Heigl Foundation, which the actress developed with her mother. The foundation has funded spay/neuter programs and also offers financial support for animal rescue organizations.

The foundation is named after Heigl's brother Jason, who died from brain damage in 1986, one week after being in a car accident.

The PSA also has a full website to go along with it called IHateBalls.com which features information about neutering pets and merchandise like "I Hate Balls" T-shirts.

The video shows Heigl holding a dog and also has the actress present reasons why she is not fond of testicles. "Unfortunately I can't cut the nuts off human men...yet. So I've dedicated my time to the neutering of dogs 'cause that's legal," she said in the video, which can be seen below.

Heigl will next appear on the big screen in "New Year's Eve" opposite rocker Jon Bon Jovi, which hits theaters on December 9. Check out Heigl's PSA below. Warning: The video contains explicit language.

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