His wife, Mariah Carey, tweeted Wednesday that Cannon, 31, is suffering from "mild kidney failure."
His representative confirmed Cannon's hospitalization in Aspen, Colo., where he and Carey were vacationing.
Cannon is in stable condition, but Carey tweeted that he's in a lot pain, saying he's suffering from "mild kidney failure."
The "America's Got Talent" host tweeted to his followers, "Currently being transferred [sic] to a hospital in LA. Thank you all for all your love, prayers and concern. You know me... I will be a'ight."
Carey asked for prayers and said Cannon's situation was "very painful." She later called it a "serious moment that's very tough on all of us."
The two became parents of twins, a boy and a girl, last year.