The award, given on the day before the 125th anniversary of Hollywood, is to celebrate movie making in the city.
Two French stars and one director from France are celebrating their American movie. "The Artist" was made in Hollywood, and the city of Los Angeles is thrilled to honor what that means to the industry town.
"To have that kind of response is very touching and very moving for me because this movie has been like a love letter to Hollywood," said director Michael Hazanavicius.
Actress Penelope Ann Miller pointed out that of the nine movies up for best picture for the Academy Awards, "The Artist" was the only one filmed completely in Hollywood.
One of the scenes in "The Artist" was shot at Hollywood's Red Studios.
While the "Made in Hollywood" honor is something new, one of the film's most popular stars is officially old and heading toward retirement.
Uggie's trainer Omar von Mueller said the dog is 10, so he won't be doing anymore long movies. But before Uggie retires, he's up for two Golden Collar awards, which will be handed out next month.