That home invasion robbery took place about 4:30 a.m. in the 900 block of Linda Flora Drive.
Police said the suspects kicked in the front door and tied up the man, a longtime collector of vintage cars and motorcycles.
The man's wife was able to get away and went to a neighbor's house to call police.
Police said the suspects knew exactly what they were after. They went straight for the two vintage motorcycles valued at more than $1.5 million.
One of the motorcycles was a rare 1914 yellow Cyclone. The other was a 1952 gray and red Kawasaki.
The wife said the thieves loaded the motorcycles onto a white van, possibly a rental.
"It's a quiet, residential neighborhood, but we don't think it was a random break-in," said neighbor Charles Lesser. "It looks as if whoever did it knew exactly what they were looking for and took it and left."
Anyone with information is asked to call the Los Angeles Police Department at (877) 527-3247.