A female audience member wrote anonymously on blog that Tosh "started making very generalizing, declarative statements about rape jokes always being funny, how can a rape joke not be funny, rape is hilarious."
The woman says she then yelled out, "actually rape jokes are never funny." She said Tosh then said it would be funny if she was raped.
Comedian Dom Irrera watched it happen.
"Do you think all the things we say we mean, do you think he really thought that? How stupid is the overreaction to this? You might as well say that about all comedy then," Irrera said.
Tosh tweeted, "All the out-of-context misquotes aside, I'd like to sincerely apologize."
Tosh also hosts the Comedy Central television show "Tosh.0."