The City Council made the decision on Wednesday as the city faces a $45.8 million budget shortfall.
Some jobs eliminated are positions within the San Bernardino Police Department. Cutbacks could also close three of the city's four libraries.
The council also voted to slash $20 million from the city's $166 million budget.
San Bernardino filed for Chapter 9 bankruptcy on Aug. 1. It is the third California city to file for bankruptcy this summer.