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OTRC: Giuliana Rancic talks motherhood, night feedings and baby on 'Today' - See video

Giuliana Rancic appears on the 'Today' show on September 19, 2012. (NBC)

Giuliana Rancic gave her first live interview since welcoming her son Edward Duke Rancic on August 29, and is looking back at 2012 as both the best and worst year of her life.

"In one year, so much has happened," Rancic said in an interview on the "Today" show on Wednesday, September 19. Video from the interview can be viewed below.

"This was the best year of my life because of the baby and it was the worst year of my life because of the breast cancer," she added. "But it just goes to show that if you're strong and you're positive, great things can come out of the darkest time in your life."

Rancic and her husband Bill Rancic struggled to have children for years. Rancic had a miscarriage in 2010 and also attempted two vitro fertilization (IVF) treatments. She was diagnosed with breast cancer during a doctor's appointment to discuss a third. She underwent a double mastectomy in December 2011.

She made an appearance on the "Today" show to raise awareness for Do it for the Girls Day on Thursday, a nation-wide campaign to promote early detection of breast cancer.

"We're encouraging women to give themselves a breast self exam and really think about early detection," Rancic explained. "Early detection is everything. It's what saved my life. If you detect breast cancer early, you have a 98 percent five-year survival rate."

Rancic also spoke about the woman who was the gestational carrier of her baby.

"She gave us the greatest gift in the world," Rancic said. "When he came into the world it was like we just started hysterical crying tears of joy. It was pretty emotional."

Rancic also said viewers will not hear any complaints about late night feedings from her or her husband.

"Bill and I fight over who's going to feed him, just because we struggled so long to have a baby that now that he's here, we're not going to complain," she said. "You're never going to hear us complaining. I just love spending every second I can with him."

Check out Giuliana Rancic's interview on the "Today" show below.

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