Neve Campbell is reportedly stopping by Seattle Grace.
The actress will play one of Dr. Derek Shepherd's sisters for two episodes of "Grey's Anatomy," according to TV Line. The report notes that Dr. Shepherd has four sisters, two of which have already been seen on the series or its spin-off "Private Practice."
Caterina Scorsone plays Amelia Shepherd on "Private Practice," while Embeth Davidtz guest starred as Shepherd's sister Nancy. Dr. Shepherd also has a yet-to-be seen sister named Kathleen who is a psychiatrist and an unnamed fourth sister.
Patrick Dempsey stars in the series as Dr. Derek Shepherd and he and Campbell, 39, previously starred in "Scream 3" together where he played a love interest of her infamous Sidney Prescott character. Campbell revived the role in 2011 for "Scream 4" and currently stars on the 12-hour miniseries "Titanic: Blood and Steel."
The actress rose to fame playing Julia Salinger on the 1990s drama series "Party of Five" and starred in all four "Scream" horror films. Campbell is set to star in the 2013 drama film "Vivaldi," which is about the late famed composer Antonio Vivaldi, who is played by "Red Riding Hood" actor Max Irons.