Gwyneth Paltrow and Cameron Diaz rap about Chelsea Hander, call her a "ho" who drinks too much.
In the rap, which was performed to congratulate Handler on moving into a new studio for her "Chelsea Lately" series, the actresses referred to themselves as M.C. Gwyneth Paltrow, 40, and DJ Jazzy Cameron Diaz, 40.
Diaz takes on the task of beat boxing, while Paltrow raps that Handler "got on TV by being a ho," referring to Handler's past four-year relationship with Ted Harbert, chairman of NBC Broadcasting, which merged with Comcast, owner of E! Entertainment Television. The two ended their four-year relationship in early 2010.
Paltrow went on to say, "We kind of like you 'cause you're blonde like us, but we can't hang with you in public 'cause you drink too much!"
The pair closed the performance with a reference to the 37-year-old TV host's fling with rapper 50 Cent, joking that they heard that she "liked it rough."
The only man in Handler's life that the pair didn't reference was her most recent boyfriend, Andre Balazs, 55, who heads a company which owns several hotels including the Chateau Marmont and The Standard hotels in Los Angeles and has been linked to Uma Thurman and Courtney Love.
Handler and Balazs reportedly split in November and reconciled briefly in May, before parting ways again.
Handler and Diaz recently helped Paltrow celebrate her 40th birthday in New York City.
Watch a clip from Gwyneth Paltrow and Cameron Diaz's rap below.