The female mountain lion, which biologists said was approximately one-year-old and had been dead for about a week, was known as Puma-25.
Its remains have been transferred to the California Animal Health and Food Safety Laboratory for a necropsy.
"Mountain lions in the Santa Monica Mountains face a number of challenges to survive," said Dr. Seth Riley, an expert on urban wildlife with Santa Monica Mountains National Recreation Area (SMMNRA). "In addition to conflicts with other lions over territory, lions here have to contend with road mortalities, rodenticide poisoning and occasionally disease."
Biologists say the lion's death does not appear to be the result of a conflict with another lion.
The results of the necropsy will be available in the next few weeks.