Police were called to an accident near Griffith Avenue and 22nd Street Sunday around 12:31 a.m.
When officers arrived at the scene, they found an 8-year-old boy and his parents trapped inside a white Dodge Durango. According to authorities, a black Cadillac Escalade T-boned the family's vehicle while traveling 70 miles per hour.
One person had to be cut out of the SUV, officials said.
The boy was transported to University of Southern California Medical Center where he is listed in critical condition but expected to survive.
His parents are in fair condition.
The driver of the Escalade was transported to the hospital for moderate injuries and arrested on suspicion of DUI.