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OTRC: Michael J. Fox set to star as newscaster in new NBC comedy series (Poll)

Actor Michael J. Fox attends 'A Funny Thing Happened on the Way To Cure Parkinson's' Michael J. Fox Foundation for Parkinson's Research benefit at the Waldorf-Astoria Hotel on Saturday Nov. 10, 2012 in New York. (Evan Agostini / AP)

Michael J. Fox is making his grand return to television, and this time, it's personal.

In the actor's upcoming NBC comedy, which is currently untitled, Fox will play a newscaster who quits his job because of Parkinson's Disease, but returns to work in the show's first episode because a new medical regimen has helped him control many of the disease's symptoms, according to the Associated Press.

In the family comedy, Fox's character will be the father of two teen-age children and a younger boy, Jennifer Salke, the network's entertainment president, said on Sunday. It will be set in New York City, and filmed there as well, according to AP.

"It's a family show that has him dealing with work and office relationships as well as dealing with kind of his public persona, which is very real," Salke explained. "You see, he gets a standing ovation everywhere he shows up, and the idea that he's sort of been put up on this pedestal by the country and the world, really. He's just a regular guy, who gets frustrated, who gets mad at having to sit at home."

While the NBC fall schedule is not set yet, the network is aiming to put it on Thursday night, where "30 Rock" and "The Office" are set to end in the next few months.

In September, Fox talked to Ellen DeGeneres on her daytime talk show about the NBC comedy pickup, joking: "They're crazy."

The 51-year-old left the ABC sitcom "Spin City" in 2000 to spend more time with his family and focus on finding a cure for Parkinson's disease. He was diagnosed with the ailment in 1991 and founded the Michael J. Fox Foundation for Parkinson's Research, the largest private funder of Parkinson's disease research worldwide.

"They're crazy," Fox told Ellen DeGeneres on her talk show on Sept. 19, 2012, after she mentioned that NBC bought the episodes without seeing any scripts. "It's a big leap of faith."

NBC announced on August 20 that the network has given a straight-to-series, 22-episode order for a comedy series the actor had pitched that is loosely based on his life. He will play a husband and father of three kids from New York City who tries to deal with family, career and Parkinson's disease. The show will be a single-camera series and will begin filming this year. It is set to premiere in the fall of 2013.

The actor rose to fame in the 1980s, playing young Republican Alex P. Keaton on the NBC sitcom "Family Ties." He later became famous for his role as Marty McFly in the "Back To The Future" movies. After he quit "Spin City," he continued to act sporadically. In 2011, he played himself on an episode of HBO's "Curb Your Enthusiasm," which earned him his 14th Emmy nomination. In September, at the Creative Arts Emmys, Fox lost to Jimmy Fallon. He won for an "SNL" guest spot.

Fox won three Emmys for his role on "Family Ties," one for his lead part in "Spin City" and one for a guest spot on the FX series "Rescue Me" in 2009. Since late 2010, Fox has had a recurring role on the CBS series "The Good Wife," for which he was nominated for two Emmys.