Police say a vehicle drove by and someone inside shot the teens, aged 15, 16 and 17, at 53rd and Figueroa streets.
The incident happened at about 9:30 p.m. Saturday.
One of the boys was reported to be in critical condition after he was shot in the chest. The other two were treated for an arm injury and a back wound.
Police believe the shooting was gang-related. No one has been arrested.