The incident occurred on the 900 block of Olympic Boulevard near Alameda Street at Sam's Hofbrau at about 3:30 a.m. Sunday.
Investigators say a fight broke out inside the club between a man and two other men. The fight escalated and spilled outside. That's when police say the suspect, identified as 40-year-old Terrence Meeks, got into his white BMW and slammed into the two men as they were heading for their Mini-Cooper. Authorities say the men were pinned between the two cars.
They were both rushed to the hospital in stable condition. Doctors told police that one victim would have both legs amputated above the knee, and the other man would have his right leg amputated above the knee.
The names of the victims were not immediately released. One victim is described to be in his 20s and the other in his 30s.
Meeks was taken into custody. He was expected to be booked on two counts of attempted murder and DUI, said officials.
City News Service contributed to this report.