The crash occurred at about 7:43 p.m. on Avenue L.
The victim was crossing the street when she was hit by an unknown type of vehicle traveling eastbound on Avenue L.
The suspect did not stop and was last seen fleeing eastbound.
The unidentified victim was transported to a nearby hospital with serious injuries.
Anyone with information regarding this hit-and-run was asked to contact the Lancaster Sheriff's Station Traffic Enforcement Team at (661) 948-8466 or Crime Stoppers at (800) 222-TIPS.