Police have arrested the 52-year-old homeowner, Ariel Castro, along with his two brothers, but have not said what charges they're facing. Castro's relation to the women was unclear.
Authorities said Amanda Berry, Michele Knight and Gina DeJesus were found in a residential area a few miles from where they disappeared. All three women appeared to be in good health and were reunited with loved ones, police said. They had been held at the home, often tied up, since their disappearance, investigators said.
Berry went missing when she was 16 on April 21, 2003. She had called her sister to say she was getting a ride home from her job at a Burger King but never came home. DeJesus went missing at age 14 on her way home from school about a year later. Knight, who was 20 at the time she disappeared, was last seen leaving her cousin's house in 2000.
Residents in the Cleveland neighborhood had no idea the women were living on their street, until Charles Ramsey heard screams for help coming from his neighbor's house.
"She says, 'Call 911, my name is Amanda Berry,'" Ramsey said. "When she told me, it didn't register until I got to calling 911. I'm calling 911 for Amanda Berry? I thought this girl was dead."
Ramsey and Berry called 911. Before officers came to her aid, Berry told the dispatcher to get police there immediately, fearing a man would soon return to the home.
When police arrived to the home, they found all three women, along with Berry's 6-year-old daughter. Neighbors said they thought Castro lived alone.
The women were being evaluated at a Cleveland hospital Monday night, where well-wishers cheered during a news conference. The emergency room doctor treating the women and Berry's daughter said they all appear to be in fair condition.
The FBI has obtained a warrant to search Castro's house. According to his uncle, Castro worked for the Cleveland School District as a bus driver.
A press conference was expected to be held late Tuesday morning to provide more details surrounding the missing persons investigations.