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OTRC: Oprah returns to acting in 'The Butler' - See video

Oprah Winfrey appears in still from "The Butler" trailer, which was released in May 2013. (The Weinstein Company)

Will Oprah earn another Oscar nomination?

The Queen of Media returns to acting in "The Butler," a historical drama directed by Lee Daniels, of "Precious" fame.

Winfrey, who posted an on-set Instagram of the production in September 2012, portrays the wife of Cecil Gaines, an African American man who works his way from a laborer on a cotton farm to the position of butler at the White House. The film, which stars Forest Whitaker as Gaines, is based on the real-life story of Eugene Allen, who served as butler for eight American presidents until his retirement in 1986.

The recently released trailer depicts an emotional biopic, in which the viewer witnesses four decades of American history, including the Civil Rights movement and the assassination of Martin Luther King, Jr., through the eyes of the butler and his family.

The film also stars Robin Williams as Eisenhower, Melissa Leo as Mamie Eisenhower, James Marsden as Kennedy, Minka Kelly as Jackie Kennedy, John Cusack as Richard Nixon, Alan Rickman as Reagan and Jane Fonda as Nancy Reagan.

Written by Danny Strong -- the Emmy Award-winning screenwriter of "Recount" and "Game Change" -- the project also features the acting talents of Cuba Gooding, Jr., Lenny Kravitz, David Oyelowo, Vanessa Redgrave, Live Schreiber, Alex Pettyfer, Jesse Williams, Mariah Carey and Colman Domingo.

This is Oprah's first performance in a feature length film since her lead role as Sethe in the 1998 movie "Beloved," which was based on the book by Toni Morrison. The media maven has also starred as a voice actress for films such as "The Princess and the Frog," "Bee Movie" and "Charlotte's Web."

"The Butler" is set to be released on Oct. 18, 2013. Watch the trailer below.

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