Jolie stunned the world when she revealed she had both of her breasts removed due to the BRCA1 gene that puts her at high risk of developing breast and ovarian cancer.
Sources tell ABC News that Jolie will now have her ovaries removed as well -- and as soon as possible. It's a move that nearly 70 percent of those who test positive for BRCA do.
Both Jolie's mother and maternal grandmother had ovarian cancer, which is called the silent killer. Ovarian cancer has claimed the lives of over 140,000 American women in the last decade.
But there are risks involved with ovarian removal, including early menopause, heart disease and routine surgical complications.
ABC News contributed to this report.