That number is up from last year, when 119 people were arrested.
Law enforcement officers will be out in force throughout the remainder of the Fourth of July weekend, looking for drivers who may be under the influence or violating other traffic laws.
The Los Angeles Police Department will be conducting saturation patrols in the Newton area Saturday from 5 p.m. to 1 a.m. in the Southeast area of South Los Angeles.
The California Highway Patrol's "maximum enforcement period" began at 6 p.m. Wednesday and will continue through 11:59 p.m. Sunday. Officers will look for motorists who are driving drunk, but will also focus on reducing problems caused by aggressive driving, an official said.
Also helping to patrol for drunken drivers throughout Los Angeles County is the "Avoid the 100 DUI Task Force," which is made up of representatives from several local police departments.
City News Service contributed to this report.