Cranston has won three Emmy Awards for his role in the AMC drama. He also received a best supporting actor in a comedy nomination for his work on "Malcolm in the Middle."
Cranston's longtime friend, actor John O'Hurley, his former TV wife from "Malcolm in the Middle" Jane Kaczmarek and his current "Breaking Bad" co-star Aaron Paul celebrated with Cranston at the ceremony on Tuesday.
Cranston thanked his fans for his success on the show, in which he portrays a straight-laced high school chemistry teacher-turned-methamphetamine manufacturer Walter White.
The actor's early TV appearances include "Airwolf," "Murder, She Wrote," "Hill Street Blues," "Falcon Crest" and "Baywatch," the made-for-TV movies "The Return of the Six-Million-Dollar Man and the Bionic Woman" and "I Know My First Name is Steven," and the miniseries "North and South, Book II."
His first prime-time role was in the short-lived 1988 CBS comedy "Raising Miranda," and he also appeared six times on Seinfeld in the 1990s.
Cranston's movie credits include the 2012 best picture Oscar winner "Argo," the 2012 remake of "Total Recall," "Saving Private Ryan," "Rock of Ages," "Drive," "Little Miss Sunshine," "Contagion," "John Carter," "The Lincoln Lawyer" and "That Thing You Do!'
He is in production on the remake of "Godzilla," set to be released next spring.
City News Service contributed to this report.