The assault happened around 12:30 a.m. Saturday in the 44200 block of Division Street.
The victim, whose name has not been released, was transported to a hospital. He later died from a head injury.
A man was taken into custody. Authorities said they are withholding the suspect's identity due to the ongoing investigation.
Anyone with information about this case was asked to contact the Los Angeles County Sheriff's Department's Homicide Bureau at (323) 890-5500 or Crime Stoppers at (800) 222-8477.