Pinette was found dead in his hotel room on Saturday at the Pittsburgh Sheraton. The medical examiner's office says his death was due to natural causes.
Pinette, known for his impressions and self-deprecating jokes about his size, appeared in several movies, including "Duets," "The Punisher" and "Junior."
He also guest-starred on the series finale of "Seinfeld," as a carjacking victim whose plight lands the cast members in jail. Pinette also appeared in the television series "Parker Lewis Can't Lose."
His agent, Nick Nuciforo, said Pinette had been working on another stand-up project when he died.
The Associated Press contributed to this report.