The crash, involving a big rig, pickup truck and a van, was reported just before the northbound 2 Freeway at about 5:20 a.m. Four of five lanes were blocked for nearly two hours.
Crews worked to move the overturned van, which caught fire after the collision. All lanes reopened at 7:05 a.m.
CHP Officer Alex Rubio said no injuries were reported. The cause of the crash has not been determined.
City News Service contributed to this report.