The crash happened near 54th and Figueroa streets at about 6:45 p.m., according to Los Angeles Police Department officials.
Los Angeles Fire Department officials said three people were critically hurt and one other person declined transport to a hospital.
A 2-car crash critically hurts 3 people at a South LA bus stop. One driver flees the scene. The story at 10 & 11pm. pic.twitter.com/l66UEwKCjJ— Melissa MacBride (@abc7melissa) September 27, 2016
Those critically injured were identified as a man and woman, both in their 70s, and a woman in her 50s, police said. Authorities initially described the victims were members of the same family; a police spokesman later said that information could not be confirmed.
LAPD Media Relations officials said the elderly man subsequently died from his injuries.
A driver crashed his vehicle and caused another vehicle to plow into the three victims, according to officials. The suspect then ran away, and police said the driver of the second vehicle stayed at the scene.
The suspect remained at large.