The blaze was reported around 1 p.m. at 2580 N. Soto St. near Mission Avenue. No structures were threatened, according to the Los Angeles Fire Department.
Fire officials launched a ground and aerial response to the fire, which was consuming medium-level grass.
The LAFD was assisted by crews from the Los Angeles County Fire Department.
The University of Southern California sent a campus alert to inform students at its Health Sciences Campus about the blaze.
According to the university, the northbound lanes of Soto Street were closed near the scene.