Investigators say the woman was able to remove the handcuffs and dropped them in a police station parking lot.
Calderon is currently on probation for grand theft. She was last seen wearing a green shirt, pants, and no shoes.
She's described as African-American with short, cropped black hair and brown eyes. She's 5 feet 5 inches tall and weighs 145 pounds.
Anyone with information on her whereabouts is asked to call Hollywood Division detectives at (213) 972-2922 or 2925.